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Dr. Hamid Ghandehari
Center for Nanomedicine and Cellular Delivery
University of Maryland School of Pharmacy
Abstract
Nanostructures for Targeted Drug Delivery: Can We Do Better?
Design and development of novel systems that deliver therapeutics or diagnostics to the diseased site improve efficacy and reduce toxicity of treatment for patients. This can be done by modifying existing well-established carriers or by exploring the potential of new nanoconstructs made possible by advances in nanotechnology. In this talk using examples such as N-(2-hydroxypropyl) methacrylamide copolymers, poly amido amine dendrimers, recombinant polymeric gene carriers, and silica nanotubes studied for targeted delivery to solid tumors in our lab, the influence of control over carrier structure on improving delivery will be discussed.
Biography
Dr. Ghandehari received his BS in Pharmacy (1989) and PhD in Pharmaceutics & Pharmaceutical Chemistry (1996) both from the University of Utah, Salt Lake City, Utah. He is currently Associate Professor of Pharmaceutical Sciences and Director of Center for Nanomedicine and Cellular Delivery at the University of Maryland, Baltimore. The focus of his research is on novel methods of controlled drug delivery using polymeric biomaterials. He is author of more than 50 publications, Executive Editor of Advanced Drug Delivery Reviews, Associate Editor of Journal of Drug Targeting, member of Board of Directors of the American Academy of Nanomedicine and on advisory boards of several other organizations. Current work in his lab is funded by grants from National Institutes of Health, National Science Foundation, Department of Defense, Maryland Industrial Partnership and several other agencies.
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